Assessment of serum vitamin D levels in Egyptian children with beta-thalassemia major

Abstract Background Beta-thalassemia major patients are at increased risk of complications including endocrinopathies and bone disease due to iron overload. So, this study aimed assess the growth parameters, serum levels 25-OH-vitamin D, calcium, phosphorous in children with beta-thalassemia major. This was a case-control that included 55 compared 30 sex- age-matched healthy served as control group. All enrolled were subjected full history taking, clinical examination anthropometric measurements, laboratory investigations complete blood count, ferritin, phosphorus, D. Results Body mass index statistically significantly lower thalassemic group ( P < 0.001). It observed vitamin D than controls value .0001). The mean 19.84 ± 5.79 ng/ml 44.98 5.77 ng/ml, respectively; 22 cases (40%) had insufficient 5 (9%) deficient Regarding calcium phosphorous, there no significant difference between groups. Conclusion Children low body metabolic abnormality form signify importance therapeutic interventions.